Special education researchers conduct studies that can be considered replications. However, they do not often refer to them as replication studies. The purpose of this article is to consider the potential benefits of conceptualizing special education intervention research within a framework of systematic, conceptual replication. Specifically, we advocate for the value and importance of replication research that includes both closely aligned and distal conceptual replications. We acknowledge the challenges associated with conducting replications in applied school-based research and also provide recommendations for how to design, conduct, and report replication studies in special education research with the goal of supporting the identification of effective practices for individuals with disabilities.