An observer-based dynamic output feedback H controller is proposed for a class of two-dimensional (2D) uncertain discrete systems described by the Roesser model with actuator saturation, time-varying state delay and external disturbances. First, a delay-dependent Lyapunov stability condition is derived in linear matrix inequality (LMI) form which uses the reciprocal convex approach and H disturbance attenuation performance is also analysed. Secondly, a convex hull is adopted to represent the saturation nonlinearity. The H control synthesis for uncertain 2D discrete systems is described by a Roesser model subjected to actuator saturation and external disturbances using an observer-based dynamic output feedback approach. Some practical examples are provided to highlight the usefulness of the presented results.