This article sought to understand the association between employee satisfaction with several family-friendly programs and turnover in U.S. federal agencies. It also built on previous cross-sectional studies that examined the relationship between these benefits and both attitudes and outcomes. More specifically, this article used social exchange theory to develop hypotheses regarding the effect of telework, alternative work schedules, child care subsidies, elder care, employee assistance programs, and health and wellness programs on turnover. Furthermore, 4 years of panel data were obtained from the Federal Employee Viewpoint Survey and FedScope to test the hypotheses. Consistent with social exchange theory, results from the balanced panel model indicate that satisfaction with family-friendly programs in general had a significant, negative effect on turnover. The results also indicate that telework, alternative work schedules, child care programs, and health and wellness programs reduced turnover. Telework, employee assistance programs, and health and wellness programs were significant at the .10 level. Elder care programs, on the other hand, were not found to have an impact on turnover. The implications the results have for theory and practice are discussed in the article.