Theories of youth resilience neglect youths’ lived experiences of what facilitates positive adjustment to hardship. The Pathways-to-Resilience Study addressed this by inviting Canadian, Chinese, Colombian, New Zealand and South African (SA) youths to share their resilience-related knowledge. In this article I report the challenges endemic to the rural, resource-poor, South African research site that complicated this Pathways ideal. I illustrate that blind application of a multi-country study design, albeit well-designed, potentially excludes youths with inaccessible parents, high mobility, and/or cellular telephone contact details. Additionally, I show that one-on-one interview methods do not serve Sesotho-speaking youths well, and that the inclusion of adult ‘insiders’ in a research team does not guarantee regard for local youths’ insights. I comment critically on how these challenges were addressed and use this to propose seven lessons that are likely to inform, and support, youth-advantaging qualitative research in similar majority-world contexts.