The global financial crisis that spread from the United States to Europe severely impacted Greece. This is a study of quality of life (QoL), anxiety, depression, and stress in Greece following the austerity measures imposed after the crisis. A convenience sample of 901 adults completed (1) a brief survey form, (2) the Multicultural Quality of Life Index (MQLI), and (3) the Depression Anxiety Stress Scales (DASS). Results indicated higher DASS scores in comparison to other normative populations. Overall, QoL in Greece is lower for women, those who are single, the unemployed, and those with lower incomes. Implications for social work practice and the profession are discussed.