The purpose of the study was to examine the effects of auricular acupressure for smoking cessation on male college students. The experimental group (n = 27) received auricular acupressure on specific acupoints for smoking cessation, whereas the control group (n = 26) received sham auricular acupressure on nonspecific acupoints. Participants received 6 weeks of auricular acupressure intervention. For the experimental group, auricular acupressure was applied to the shenmen, lung, subcortex, hunger, stomach, and mouth. The data of nicotine dependence, self-efficacy for smoking cessation, and exhaled carbon monoxide were collected for both group 3 times: before intervention, after 3 weeks of the intervention, and after 6 weeks of the intervention. Statistical differences between the two groups from pretest to posttest emerged in self-efficacy for smoking cessation (p = .048) and exhaled carbon monoxide (p < .001), but not for nicotine dependence.