Research often characterized as "new materialist" has staged a return/turn to nature in social and critical theory by bringing "matter" into the purview of our research. While this growing impetus to take nature seriously fosters new types of interdisciplinarity and thus new resources for knowing our nature-cultural worlds, its capacity to deal with power’s imbrication in how we understand "nature" is curtailed by its failures to engage substantively with the epistemological interventions of postcolonial feminist science studies. The citational practices of many new materialist thinkers eschew the existence of what Sandra Harding has called "a world of sciences." I argue that the "science" privileged and often conflated with matter in new materialist storytelling is the same science destabilized by postcolonial feminist science studies. This does not mean that new materialist feminisms and postcolonial feminist science studies are necessarily at odds, as new materialist storytelling and prevailing conceptualizations of the postcolonial seem to suggest. On the contrary, I suggest that thinking creatively, capaciously, pluralistically, and thus irreverently with respect to the rules of science––about the boundaries and meanings of matter, "life," and "humanness"––could be understood as a central project for a postcolonial feminist science studies.