Across many sectors, new developments and discourses that emphasize change, collaboration, shifting professional boundaries and increased sharing of knowledge are taking place. One is thus challenged to question and/or develop further understanding of how and to what extent new ideas, scientific developments and technologies are translated within such contexts and thereby extend management and organization studies. To advance understanding about this significant field in the scholarly community, this special issue has assembled a diverse set of papers, which review developments in translation theory and seek to encourage new thinking and frameworks and open up new directions in management and organization studies more generally. By reflecting on these papers, the authors summarize key challenges in translational research and new framings, and point to exciting new research opportunities that can be found in fruitfully comparing, elaborating, expanding, contrasting and blending extant perspectives.