Using data generated from the Global Risk Assessment Device, mental health and disrupted family processes were examined in a sample of 166 court-involved youth being raised by grandparents. Race and gender mean differences were found with regard to both mental health symptoms and disrupted family processes. Specifically, Caucasian male adolescents reported higher mental health symptoms and disrupted family processes than African American males. Also, females in the sample generally reported higher disrupted family processes than males, with African American females reporting significantly higher average disrupted family processes than African American males. Despite mean differences associated with gender and race, when entered as predictors, neither main effects nor interactions of gender or race were related to mental health symptoms. Disrupted family processes were predictive of higher mental health symptoms. Family-targeted interventions with court-involved youth being raised by grandparents would likely benefit the mental health of these adolescents.