The authors review research that has used social cognitive career theory as a frame to investigate factors that may explain science, technology, engineering, and mathematics (STEM) choices and work decisions for women and racial–ethnic minorities, as well as barriers to their entry to STEM careers. The research is reviewed by age-groups. Most of this research has focused on factors associated with early choices (e.g., in high school and younger), but more recent work has focused on choices in college and in the workplace, particularly for women. The authors conclude with a critique and call for more research.