Objectives: This meta-analysis examines the strength of the link between substance use (e.g., alcohol use vs. drug use) and intimate partner violence (IPV) perpetration and victimization. Method: Data from 285 studies (yielding 983 effect sizes (ESs) and a combined sample size of 627,726) were analyzed using random effects. Moderator analyses compared the impact of overall substance abuse, alcohol use, and drug use on IPV perpetration and victimization for males and females. Results: Overall substance use, alcohol use, and drug use were significantly related to IPV perpetration and victimization, with mean ESs ranging from r = .18 to .23. Results indicate that drug use is a significantly stronger correlate with victimization, compared with alcohol use. Problematic alcohol use measures (i.e., abuse, dependence, and drinking problems) were significantly stronger correlates than consumption measures (e.g., alcohol use or frequency) for IPV victimization, but statistically similar for IPV perpetration. Problematic drug use measures were significantly stronger correlates with perpetration than drug consumption measures. Surprisingly, there were no significant differences between the impact of different drug types, and no significant difference between the impact of stimulants versus nonstimulants on IPV perpetration and victimization. Conclusions: This study provides the most comprehensive analysis of the link between substance use and IPV to date. Even if certain drugs are regarded as a lower health risk, clinicians are encouraged to evaluate the impact on their clients’ IPV. Future IPV researchers are encouraged to include specific drug types and frequencies of substance use. (PsycINFO Database Record (c) 2016 APA, all rights reserved)