This article draws on the notion of ‘cultural defense’ to examine how nationalism shapes contemporary contestations around religion and secularity in Armenia. While clearly relevant, this framework has rarely been used for the analysis of religious change in the Caucasus region as part of the broader post-Soviet space. This article fills this lacuna. Simultaneously, it moves beyond the relatively narrow interest in the degree of secularization or reinforced religious nationalism as social outcomes of cultural defense situations. Instead, we are interested in how boundaries between religion and secular spheres in society are drawn in particular ways, how the resulting religious – secular configurations have evolved since the end of the Soviet Union – of which Armenia was a part – and how concepts of nationhood and nationalist mobilizations have shaped this process.