The stability problem of nonlinear time-delay systems is addressed. A quadratic constraint is employed to exploit the structure of nonlinearity in dynamical systems via a set of multiplier matrices. This yields less conservative results concerning stability analysis. By employing a Wirtinger-based inequality, a delay-dependent stability criterion is derived in terms of linear matrix inequalities for the nominal and uncertain systems. A numerical example is used to demonstrate the effectiveness of the proposed stability conditions in dealing with some larger class of nonlinearities.