In recent discussions on local sustainable development, notions like “local for local” and “home bias” have often played a role. The purpose of this paper is to investigate whether preferences for specific place‐based attributes might constrain or support tourism participation and tourism destination choice of distinct socioeconomic groups of visitors. To test this proposition, a large data set from the Italian Households Budget Survey for the period 1997–2007 has been used and, by means of the double‐hurdle model, tourism participation and expenditure are modeled over the life‐cycle of tourists. These data are next merged with location‐specific attributes including natural amenities and infrastructural and regional‐economic context variables. Our results show that location‐specific or place‐based characteristics affect intra‐ and interregional tourism differently, as well as destination choices. Regional differences between residents in two different macroareas in Italy (North and Center‐South) are investigated. Location‐specific characteristics may be either push or constraint factors for tourism participation. For families living in the North, participation in the tourism market is supported by the tourist characteristics of their home region. For families living in the central and southern regions however, economic conditions of the area where they reside appear to be more significant.