Aims The present descriptive study was carried out to determine the relationship between health‐related quality of life, depression and awareness of home care services among elderly patients. Methods Patients aged 65 years or older staying at the surgery and internal medicine clinics were included in the study. The “Patient Introduction Form,” “Short Form‐36 Quality of Life Questionnaire” and “Geriatric Depression Scale” were utilized in the collection of data. Results In the present study, it was determined that only approximately half of elderly patients (54.9%) knew the concept of home care, most of them had not previously received home care and requested home care related to medical care. The mean scores were lower in some areas of the quality of life questionnaire in some factors that could influence home care awareness. These factors were determined as: female sex, history of falling, chronic illness, functionally, moderately or severely dependent, no previous receipt of home care and wishing to receive home care. Conclusions The home care requirement of elderly patients can be influenced by many physiological, psychological and social factors that can affect their quality of life. Thus, it is of utmost importance that medical professionals evaluate the quality of life of elderly individuals and its influencing factors. Geriatr Gerontol Int 2016; 16: 1211–1219.