--- - |2+ Objective Mindfulness‐based interventions can improve quality of life (QoL) in people with multiple sclerosis (PwMS); however, the potential benefits of brief mindfulness group programs delivered in community settings have not been investigated with this population. This pilot study evaluated a brief (five‐session) community‐based group mindfulness program for PwMS. Method Participants were 23 PwMS recruited through Multiple Sclerosis Queensland, Australia. The study had a single intervention condition with pre‐intervention, post‐intervention and eight‐week follow‐up assessments. Primary outcomes were QoL, psychological distress and fatigue, and secondary outcomes were mindfulness, self‐compassion, and acceptance. Results Analyses revealed improvements in psychological distress, perceived stress, the mental health QoL dimension, mindfulness, self‐compassion, and acceptance. All participants agreed they would recommend the program to others with multiple sclerosis and most reported that the program was helpful and enjoyable. Qualitative data showed that participants gained in present moment awareness, coping skills, self‐compassion, acceptance, support, and changed perspectives. Conclusions Results suggest that brief mindfulness interventions may improve psychological wellbeing in PwMS; however, a longer intervention period or programs that incorporate mindful movement activities may be needed to bring about improvements in physical health QoL dimensions and fatigue. - Clinical Psychologist, Volume 22, Issue 2, Page 182-191, July 2018.