The Negative Outcome Expectations Scale in Engineering (NOES-E) is a 21-item measure that was developed to assess anticipated negative outcomes related to pursuing engineering. Using two samples of engineering students, exploratory (n = 256) and confirmatory (n = 1,187) factor analyses supported a four-factor model of the NOES-E. The four factors included cultural-related stressors, personal life and work balance, job characteristics, and social costs. The results suggested that the 21-item NOES-E demonstrated strong internal consistency (Cronbach’s α = .94) and construct validity by a positive correlation with a measure of engineering environmental barriers and negative correlations with measures of engineering academic satisfaction, self-efficacy, environmental supports, intended persistence, and positive outcome expectations. There was nonsignificant relation between NOES-E scores and future family consideration. Also, we found that women and transgender students reported higher negative outcome expectations in engineering than men. However, there were no significant group differences across race/ethnicity. Implications for practice, theory, and future vocational research in engineering are discussed.