This article takes a new approach to the study of college sexual assault by conducting an analysis of female students’ most recent “hookup.” By isolating a particular hookup event and examining the features of that event, I am able to examine predictors of sexual assault during hookups. My analysis focuses on the implications of alcohol consumption and knowing a male partner before a hookup, while controlling for multiple individual, school, and situational characteristics, using data from the Online College Social Life Survey collected 2005–2011. In my sample, 2.4% of women experienced sexual assault during their most recent hookup. Results show women do not experience an increased risk of physically forced intercourse until they have consumed nine or more drinks. In addition, women were more likely to report sexual assault during a hookup with a man they did not know well. Together, these findings suggest that men are more likely to assault women who are drunk, possibly because the double standard has made them respect such women less, or because they target women who are likely unable to resist or recall what happened. It also appears that the “in‐network stranger” may be the individual most dangerous to women in college hookups.