Objective The current study investigated the relationship of demographic and social ecology factors (social support and school connectedness) with acculturation of culturally and linguistically diverse (CALD) youth. Method Participants comprised of 237 CALD youth, from migrant and refugee backgrounds, attending a specialised Australian school designed to address English language development and re‐settlement needs of CALD youth. Results Hierarchical regression analyses revealed that after controlling for demographic factors, school connectedness and social support explained a significant percentage of the variance. Conclusion This study has implications for assisting CALD youth in schools. Findings highlight the need for further research exploring the modifiable factors that promote school connectedness and social support. Interventions and effective practices that enhance school connectedness and social support for CALD youth are identified as likely to contribute to successful acculturation.