--- - |2+ Abstract Objective Interpersonal dysfunction is an important marker of individual differences in personality and well‐being. Existing research on interpersonal dysfunction focuses primarily on the problematic behaviors of individuals without considering how sensitivity to others’ behavior impacts functioning. In this study, we test the structure and correlates of a model of relationship dysfunction that integrates the problems individuals bring to relationships with their sensitivities to others’ behavior. We specifically examine the conjoint structure of interpersonal problems and sensitivities using a circumplex framework and associations between dimensions derived from this structure and personality, well‐being, attachment, and response style variables. Method We evaluated competing measurement models and examined validity correlations of interpersonal problems and sensitivities in two samples (Study 1: N = 955; 79.2% women; Mage = 19.43; Study 2: N = 1,005; 72.1% women; Mage = 19.77). Results Six factors capturing general (nonspecific problems and sensitivities) and stylistic (warmth and dominance for both problems and sensitivities) variation in interpersonal dysfunction were empirically distinguishable and provided incremental information about external criteria. Conclusions Results support problems and sensitivities as overlapping but distinct sources of information about interpersonal dysfunction, and they specifically suggest an integrative six‐factor model with considerable potential for future research. - Journal of Personality, EarlyView.