The hard Test Your Memory. Evaluation of a short cognitive test to detect mild Alzheimer's disease and amnestic mild cognitive impairment
International Journal of Geriatric Psychiatry
Published online on August 08, 2013
Abstract
Objective
The aim of this study is the evaluation of a novel cognitive test, the hard Test Your Memory (H‐TYM), in the detection of mild Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI).
Methods
This paper uses a prospective study in an outpatient memory clinic. We recruited 97 patients with a diagnosis of mild AD or aMCI aged between 50 and 80 years. All scored 20 or more on the mini mental state examination (MMSE). We recruited 200 controls from a similar background. The patients were given a novel short cognitive test (H‐TYM) designed to test recall of newly learnt visual and verbal material together with the Addenbrooke's Cognitive Assessment Revised, MMSE, and TYM test.
Results
Alzheimer's disease/aMCI patients completed the H‐TYM with an average recall score of 6.69 (SD 3.45); control participants scored an average of 20.4 (SD 4.54). The H‐TYM detected 95% of cases of mild AD/aMCI on the basis of an optimum cutoff point. The area under the receiver operating characteristic for the H‐TYM ratio was calculated to be 0.989 with a 95% confidence interval of 0.980–0.997.
Conclusions
The H‐TYM test has an excellent ability to discriminate between AD/aMCI cases and healthy controls. The H‐TYM is a useful tool for the detection of mild AD/aMCI, and it detects AD/aMCI in the majority of patients who “pass” the MMSE and Addenbrooke's Cognitive Assessment Revised. Copyright © 2013 John Wiley & Sons, Ltd.