Considering the higher prevalence of depression in women than in men, the study of the variables that underlie this gender difference becomes important for both the prevention and the treatment of depression. This study explores gender differences in the relationship between depressive symptoms, rumination, repressive coping, and overgeneral autobiographical memory (OGM) in a nonclinical population. There are 141 men and 148 women who completed the measures of depression, rumination, and repression, and the Autobiographical Memory Test to assess OGM. Women remembered a higher number of specific memories than men. Most importantly, results showed a different pattern of association between rumination, repression, depression, and OGM by gender. Depressive symptoms were associated with repressive coping and OGM in women. However, depressive symptomatology was related to repressive coping but not to OGM in men. These results suggest that the role of OGM in depression may be less important in men than in women. Copyright © 2014 John Wiley & Sons, Ltd.