This article documents and assesses subregional variation among white southerners in presidential voting behavior and a variety of issue attitudes. I demonstrate that whites in the South remain consistently distinct from those in the rest of the nation, but heterogeneously so: whites in the Deep South are generally far more conservative than their Peripheral South neighbors. I also assess how the region’s disproportionate concentration of born-again Christians can confound assessments of regional and state coefficients when properly accounted for in regression models. By demonstrating the continuing distinctiveness of the white South, the significant variation present within the region, and the interrelationship of region and religion, these results have theoretical and methodological implications for the study of American politics.