Although research has been conducted on rape myth acceptance (RMA) and other factors associated with attribution formation, researchers have not yet determined how the combination of such factors simultaneously affects levels of victim blame and perpetrator blame. The current investigation recruited 221 students from an all-women’s college to examine differences in blame attributions across RMA, victim gender, and perpetrator gender, and the relationship between the two parties (i.e., stranger vs. acquaintance). Results suggested that RMA, victim gender, and perpetrator gender account for a significant amount of variance in blame attributions for both victims and perpetrators. In sum, victim blame with female perpetrators was relatively consistent across levels of RMA, but increased substantially for male perpetrators as individuals endorsed higher levels of RMA. Perpetrator blame, however, was highest with male perpetrators when individuals endorsed low levels of RMA and lowest for male perpetrators when individuals endorsed relatively higher levels of RMA. Findings demonstrate the continued influence of RMA on blame attributions for both victims and perpetrators, and the stigma faced by male victims. More research is needed on the differing attributions of male and female victims and perpetrators, as well as differing attributions based on type of relationship. Such research will lead to a better and more thorough understanding of sexual assault and rape.