The current study addressed the relationship between child sexual abuse (CSA) and perpetration of physical intimate partner violence, examining the possible mediating effect of antisocial traits and behaviors, as well as the differences in these relationships between men and women. Data came from the International Dating Violence Study. Hypotheses were tested on a sample of 13,659 university students from 68 sites and 32 countries using hierarchical linear modeling. Results indicated that CSA was significantly associated with perpetration of physical intimate partner violence for both men and women. The slope of the relationships, however, varied across sites for women. Antisocial traits and behaviors fully mediated the relationship between CSA and perpetration of physical intimate partner violence for women but only partially mediated this relationship for men. Increased focus needs to be paid to gender differences on the effect of CSA on the development of antisocial traits and behaviors, the relationship between these factors and perpetration of intimate partner violence, and the variation of these relationships across nations.