This study's goal was to conduct a preliminary test of the theory that just world beliefs can buffer against negative physiological outcomes after people experience certain types of negative life events by testing associations between just world beliefs and physiological outcomes among people with different life event histories. In a sample of 247 adults (Mage = 46.01; 24.31% men; 60.78% White), this research investigated the relationship between just world beliefs and metabolic symptoms, inflammation, and sleep among people who had recently experienced an unfair event, another type of negative event, or no negative event. Stronger just world beliefs correlated with lower metabolic risk, lower inflammation, and better sleep among people who had recently experienced an unfair event, but not among those in the other two event groups. These findings suggest that people's beliefs about the world may interact with their life experiences in ways that have implications for health‐relevant outcomes.