A randomized experimental design was used to determine the most effective intervention for enhancing cardiac rehabilitation (CR) enrollment for postmyocardial infarction and stent patients. The 104 subjects (70 males and 34 females; 23-87 years old) were patients with a discharge diagnosis of a myocardial infarction followed by a percutaneous coronary intervention, which included a percutaneous transluminal coronary angioplasty and the placement of one or more coronary stents. Regardless of the intervention, patients who received face-to-face nursing interventions were more likely to enroll in CR than were patients who had indirect interventions, ²(3) = 32.84, p < .001. Patients who experienced an entrance interview were most likely to enroll, ²(1) = 86.80, p < .001. Direct logistic regression determined that the full model was statistically significant for all predictors, ²(5), 105.56, p < .001, with the strongest predictor, the entrance interview, having an odds ratio of 1.73.