The Office for the Study of Aging (OSA) at the University of South Carolina was established in 1988 in conjunction with the founding of the South Carolina Alzheimer’s Disease Registry. Over the last 25 years, the Office for the Study of Aging has furthered its purpose through the development of research and programs for all of South Carolina’s aging population. Examples include the Placemat Strength Training Program, the Dementia Dialogues education program, and the South Carolina Vulnerable Adult Guardian ad Litem program. The work of the office is sustained through a unique government–university–community partnership that supports innovative work and provides direct lines for dissemination, translation, and implementation of programs. The office’s efforts have resulted in two state laws involving aging and older adults as well as recognition through awards and publications. The Office provides a partnership model that offers a dissemination and translation pipeline for programs to be developed, piloted, revised, and enacted into policy.