Associations between parental loss and high school (HS) completion were examined in data drawn from 1,761 male and 1,689 female offspring born in wedlock to mothers participating in a nationally representative study. Multiple logistic regression models were conducted predicting HS completion by age 19 among offspring whose parents divorced or father died, compared to offspring of continuously married parents. Models were estimated without and with adjustment for correlated sociodemographic characteristics, including maternal education and age at first childbirth and offspring age at last assessment and race/ethnicity. In unadjusted models, parental divorce predicted a 41% decreased odds of HS completion for males, and paternal death predicted a 79% decreased odds of HS completion for females. In models including sociodemographic risk factors, associations between parental divorce and paternal death reduced slightly. Findings highlight the importance of examining unique risks from paternal death versus parental divorce on educational attainment in male and female offspring.