In this article, I engage with Edward Said's Orientalism and various perspectives within the othering paradigm to analyze the emergence and transformation of radicalization discourses in the news media. Employing discourse analysis of 607 New York Times articles from 1969 to 2014, this article demonstrates that radicalization discourses are not new but are the result of complex sociolinguistic and historical developments that cannot be reduced to dominant contemporary understandings of the concept or to singular events or crises. The news articles were then compared to 850 government documents, speeches, and other official communications. The analysis of the data indicates that media conceptualizations of radicalization, which once denoted political and economic differences, have now shifted to overwhelmingly focus on Islam. As such, radicalization discourse now evokes the construct radicalization as symbolic marker of conflict between the West and the East. I also advanced the established notion that the news media employ strategic discursive strategies that contribute to conceptual distinctions that are used to construct Muslims as an “alien other” to the West.