["Journal of Research on Adolescence, Volume 36, Issue 2, June 2026. ", "\nAbstract\nThis study explores the influence of experiencing one, two or more stressful life events (SLE) in the past year in associations with adolescent sleep and depression symptomatology in the short and long term in the context of coping. Participants were 2323 Hispanic (44.1%), non‐Hispanic Black (30.5%), non‐Hispanic White (8.6%), and non‐Hispanic Asian (16.7%) eighth graders (51.1% female) from 24 public middle schools in southeast Texas in 2019. Multivariate linear and logistic regressions for the depression and sleep outcomes, respectively, were conducted while controlling for clustering in schools. Findings indicated that experiencing two or more SLEs (compared to one or none) was associated with worse adjustment in the short and longer term. Problem‐focused coping was concurrently associated with better adjustment but heightened the association between aggregated SLEs and depressive symptoms over time. Avoidant coping was not associated with adjustment longitudinally but, in the short term, it was associated with higher depressive symptoms and exacerbated the association between SLEs and depressive symptomatology. Avoidant coping was also associated with better odds of getting adequate sleep when no SLEs were experienced but conditioned the negative association between experiencing one SLE and worse sleep. Lastly, emotion‐focused coping was associated with poorer adjustment both in the short and longer term and exacerbated the negative association between SLEs on short‐term adjustment. These findings add incrementally to the literature on adolescent coping with SLEs during a time when researchers and practitioners are grappling with how best to address the increased stress and deteriorating mental health of adolescents.\n"]