Palliative Care in Heart Failure: An Updated Systematic Review and Meta-Analysis of Randomised Controlled Trials and Associations With Intervention and Patient Characteristics

Ravi Chotalia, Hasan Mohiaddin, Alisha Aggarwal, Edward Borchardt, Robert Ambrogetti, Minesh Chotalia, Iain Squire, Shirley Sze, Lincoln Heart Centre, United Lincolnshire Hospitals NHS Trust, Ross Lucas Medical Sciences Building, University of Lincoln, Cardiology Department, Glenfield Hospital, NIHR Leicester Biomedical Research Centre and Department of Cardiovascular Sciences, University of Leicester, University Hospitals of Leicester, Leicester Royal Infirmary, Birmingham Acute Care Research Group, University of Birmingham, Department of Anaesthetics and Critical Care, Queen Elizabeth Hospital Birmingham, Department of Population Health Sciences, University of Leicester

American Journal of Hospice and Palliative Medicine®

Published online on April 24, 2026

Abstract

American Journal of Hospice and Palliative Medicine®, Ahead of Print.
BackgroundSystematic reviews show palliative care improves outcomes in patients with heart failure (HF), but prior meta-analyses were not HF-specific, or explored how intervention and patient characteristics influence effectiveness, whilst new randomized ...