Physical Activity Patterns and Brain Health: A Systematic Review About Weekend Warrior vs Regular Exercise on Neuropsychiatric Disorders

Gabriel Moraes de Oliveira, Ana Beatriz Nardelli da Silva, Eduardo Silva Reis Barreto, César Romero Antunes Júnior, Emre Adalier, Fernanda Valeriano Zamora, Elizabeth Frates, Nacime Salomao Barbachan Mansur, Giovanna Medina, Massachusetts General Hospital, Harvard Medical School, Federal University of São Paulo, São Paulo, Federal University of Pará, Federal University of Bahia, University of Pavia, Rio de Janeiro State University, Rio de Janeiro, Department of Physical Medicine and Rehabilitation, Harvard Medical School, Medstar Union Memorial Hospital

American Journal of Lifestyle Medicine

Published online on February 08, 2026

Abstract

American Journal of Lifestyle Medicine, Ahead of Print.
This systematic review assessed whether the “weekend warrior” (WW) pattern of physical activity provides neuroprotective benefits comparable to regularly distributed activity. Data sources PubMed, Embase, Web of Science, and Cochrane Library were searched ...