Blood Flow Restriction Therapy Stimulates Intercellular Mitochondria Transfer and Improves Muscle Regeneration and Shoulder Function in a Murine Rotator Cuff Injury Model

Nesa Milan, Aboubacar Wague, Luke Sang, Alex Youn, Ryan Sadjadi, Yusef Samimi, Cristhian Montenegro, Miguel Lizarraga, Justin Lau, Allan I. Basbaum, Michael R. Davies, Hubert T. Kim, Brian T. Feeley, Jarret A.P. Weinrich, Xuhui Liu

The American Journal of Sports Medicine

Published online on March 09, 2026

Abstract

The American Journal of Sports Medicine, Volume 54, Issue 5, Page 1114-1125, April 2026.
Background:Rotator cuff (RC) tears are among the most common causes of shoulder dysfunction in sports medicine. Muscle atrophy and degeneration are important risk factors for RC tendon retearing and suboptimal recovery of shoulder function after tendon ...