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Regenerative Effect of Injectable Collagen Loaded With Mesenchymal Stem Cell–Derived Extracellular Vesicles in a Collagenase-Induced Tendinopathy Rat Model

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The American Journal of Sports Medicine

Published online on

Abstract

The American Journal of Sports Medicine, Volume 54, Issue 5, Page 1088-1102, April 2026.
Background:Tendinopathy remains a major clinical challenge due to the limited regenerative capacity of tendon tissue. Mesenchymal stem cell (MSC)–derived extracellular vesicles (EVs) show therapeutic promise; however, strategies to enhance their local ...