Alternative Osteoporosis Therapies After Bisphosphonate Associated Atypical Femur Fractures: A Retrospective Analysis

Andrew Ni, Azophi Moffat, Jordan Robbins, Dean Slocum, Abhi Rashiwala, Katerina Papanikolaou, Ravi Karia, Department of Orthopaedic Surgery, University of Texas Health San Antonio, San Antonio, Long School of Medicine, University of Texas Health San Antonio, San Antonio

Geriatric Orthopaedic Surgery & Rehabilitation

Published online on January 08, 2026

Abstract

Geriatric Orthopaedic Surgery & Rehabilitation, Volume 17, January-December 2026.
IntroductionBisphosphonate medications reduce the risk of osteoporotic fragility fractures; however, prolonged use increases the risk of atypical femur fractures (AFF). As the population ages and the burden of osteoporosis rises, the relative incidence of ...