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TRIM37 mitigates adriamycin-induced nephropathy by promoting PTEN ubiquitination and degradation to suppress mitochondrial apoptosis and podocyte injury

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Human & Experimental Toxicology

Published online on

Abstract

Human & Experimental Toxicology, Volume 45, January-December 2026.
IntroductionPodocyte loss or functional impairment is a key event in the pathophysiology of nephrotic syndrome (NS). NS can further progress to chronic kidney disease (CKD) and/or end-stage renal disease (ESRD). This study aimed to explore the potential ...