Successful Use of lenacapavir and cabotegravir/rilpivirine for virologic suppression in pregnancy: A Case Report

Mahima Upadhyay, Susheel Joshi, Urooj Khan, Suzanne Irani, Kaitlin Liroff, Department of Internal Medicine, Hurley Medical Center, Department of Internal Medicine, Covenant HealthCare, Oakland University William Beaumont School of Medicine, Department of Infectious Disease, Hurley Medical Center

International Journal of STD & AIDS: Clinical practice in sexual health

Published online on January 17, 2026

Abstract

International Journal of STD & AIDS, Volume 37, Issue 6, Page 671-673, May 2026.
This case report describes the first documented use of lenacapavir in the setting of Y188L NNRTI resistance mutation during pregnancy, resulting in successful maternal viral suppression and prevention of vertical transmission of HIV. A 24-year-old woman ...