Safety Assessment of Dodecanedioic Acid (Dodecanedioic Acid Disodium Salt) Using Genotoxicity and Repeated 28-day Oral Toxicological Evaluation

Deepali Sharma, Mangi Lal Choudhary, Pragati Bawankar, Sagar Kadam, Shruthy R. Prasad, Dhanashree Jadhav, Mahalakshmi Raj, Mital Ravalji, Margitta Dziwenka, Katrina V. Emmel, Department of Reproductive , Long Term Toxicology, Test Facility Management, Toxalta Consulting, KemmelCal Inc, Las Vegas

International Journal of Toxicology

Published online on March 13, 2026

Abstract

International Journal of Toxicology, Ahead of Print.
To evaluate the safety of Metabolyte™ (sodium dodecanedioate) for human consumption, results fromin vitroandin vivostudies are reported, including a bacterial reverse mutation assay, anin vitromammalian chromosome aberration test, anin vivo...