Inhibitory Effects and Characteristics of Byakangelicol on the Activity of Multiple Cytochrome P450 Isoforms

Ting Lin, Xiao He, Pingfa Lin, Ying Chang, Department of Pharmacy, Shengli Clinical Medical College of Fujian Medical University, Fuzhou University Affiliated Provincial Hospital, Pharmacology Teaching and Research Laboratory, Fujian Health College, Department of Clinical Pharmacy, th Hospital of PLA Joint Logistic Support Force

International Journal of Toxicology

Published online on October 27, 2025

Abstract

International Journal of Toxicology, Ahead of Print.
Byakangelicol, a furanocoumarin derived fromAngelica dahurica, possesses anti-inflammatory and antitumor activities. Since cytochrome P450 2A6 (CYP2A6) is the major enzyme responsible for coumarin metabolism, it is important to evaluate the effect of ...