Inhalation of Particulate-free Diesel Engine Exhaust Induces Pulmonary Histopathological Alterations in Rat Models: Role of TRPV1 Receptors and Oxidative Stress During Sub-acute Exposure

Ravindran Revand, Aditya Dontham, Swarnabha Sarkar, Abhishek Kandpal, Debabrata Dasgupta, Bahni Ray, Mayank Kumar, Asmita Patil, Department of Physiology, All India Institute of Medical Sciences, New Delhi, Department of Physiology, Government Medical College, Department of Mechanical Engineering, Indian Institute of Technology, New Delhi

International Journal of Toxicology

Published online on November 13, 2025

Abstract

International Journal of Toxicology, Ahead of Print.
Exposure to diesel exhaust air pollutants is a key environmental threat for pulmonary and cardiovascular diseases. Oxidative stress and Transient Receptor Potential Vanilloid-1 (TRPV1) receptors exhibit pivotal contributions in mediating lung injury ...