Engineered zero-order drug release from degradable PEG hydrogels – A rapamycin case study
Journal of Biomaterials Applications
Published online on January 06, 2026
Abstract
Journal of Biomaterials Applications, Volume 41, Issue 1, Page 29-42, July 2026.
This study describes the derivatization of Rapamycin (Ra) with acryloyl chloride (AcCl) and iodoacetic acid (IAA), yielding hydrolysis-susceptible esters designed for controlled drug release at physiological pH. These esters were further conjugated to ...
This study describes the derivatization of Rapamycin (Ra) with acryloyl chloride (AcCl) and iodoacetic acid (IAA), yielding hydrolysis-susceptible esters designed for controlled drug release at physiological pH. These esters were further conjugated to ...