Treatment of cartilage injury using a novel plug-type scaffold immersed in hyaluronic acid

Chuji Hirota, Kuniaki Ikeda, Takashi Ishitani, Takeru Iwata, Eichi Ito, Shunsuke Sezaki, Daisuke Morita, Yoshinori Okamoto, Hitoshi Wakama, Shuhei Otsuki, Department of Orthopedic Surgery, Osaka Medical and Pharmaceutical University, Takatsuki City, Product Development and Research Team, GUNZE Medical Limited

Journal of Biomaterials Applications

Published online on March 31, 2026

Abstract

Journal of Biomaterials Applications, Ahead of Print.
The osteochondral autograft transfer system has demonstrated potential for hyaline cartilage restoration; however, donor-site morbidity remains a considerable challenge. Therefore, we aimed to develop an innovative plug-type cartilage scaffold using ...