Se nanoparticles-coated, PLGA-based spheres for biomedical applications: Cytotoxicity, genotoxicity, oxidative stress, biodistribution, and scintigraphic study

Magdalena Stevanović, Jana Nunić, Metka Filipič, Giuseppe Digilio, Eirini Fragogeorgi, George Loudos, Group for Biomedical Engineering and Nanobiotechnology, Institute of Technical Sciences of the Serbian Academy of Sciences and Arts, Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Department of Science and Technologic Innovation, Università Del Piemonte Orientale , Amedeo Avogadro, National Center for Scientific Research , Institute of Nuclear , Radiological Sciences

Journal of Biomaterials Applications

Published online on February 09, 2026

Abstract

Journal of Biomaterials Applications, Ahead of Print.
Conventional approaches to prevent and treat diseases, particularly liver disorders, often fall short, highlighting the urgent need for innovative strategies and materials in RNA therapeutics and genetic drug delivery. This study investigates the ...