Generation of a three-dimensional retinal-like structure using a laminin-111-modified alginate layer

Samaneh Najafian, Mohammad Hossein Nasr Esfahani, Amirreza Haghighatnejad, Fereshteh Karamali, ACECR Institute of Higher Education , Isfahan Branch, Department of Animal Biotechnology, Cell Science Research Center, Royan Institute for Biotechnology, Department of Computer Engineering, Science and Research Branch, Islamic Azad University

Journal of Biomaterials Applications

Published online on January 08, 2026

Abstract

Journal of Biomaterials Applications, Volume 41, Issue 2, Page 273-284, August 2026.
AimOver the past few decades, the prevalence of visual impairments has increased substantially, and some are incurable. This study aimed to present a co-culture method that promotes the differentiation of retinal progenitor cells (RPCs) in the presence of ...