Bone microarchitecture impairment in juvenile systemic lupus erythematosus patients: A comparative study

Beatriz D. P, Erica M. Barbosa, Melissa Mariti Fraga, Jade D. Fernandez, Marcelo M. Pinheiro, Maria T Terreri, Paediatric Rheumatology Unit, Paediatrics Department, Federal University of Sao Paulo, Sao Paulo, Graduate Student at Medical School, Federal University of Sao Paulo, Sao Paulo, Division of Rheumatology, Department of Medicine, Federal University of Sao Paulo, Sao Paulo

Lupus: An International Journal

Published online on March 18, 2026

Abstract

Lupus, Ahead of Print.
Background:Juvenile Systemic Lupus Erythematosus (jSLE) is a multisystem inflammatory disease associated with bone loss. However, some patients experience fractures prior to the impairment of bone mineral density (BMD), suggesting that other bone ...