Psychosis in patients with systematic lupus erythematosus: A systematic literature review and meta-analysis

Konstantinos Parperis, Panagiotis Zis, Marina Evangelou, Avgoustina Kyriakou, Eleni Koliou, Heraklis Pantelidakis, Andreas Chatzittofis, Division of Rheumatology, Department of Medicine, University of Cyprus Medical School, Division of Neurology, Department of Medicine, University of Cyprus Medical School, Department of Medicine, University of Cyprus Medical School, Department of Neurology, Nicosia General Hospital, Department of Psychiatry, University of Cyprus Medical School, Department of Clinical Sciences, Umeå University

Lupus: An International Journal

Published online on March 10, 2026

Abstract

Lupus, Volume 35, Issue 6, Page 592-610, May 2026.
ObjectivesPsychosis is a rare but severe neuropsychiatric manifestation of systemic lupus erythematosus (SLE). Its prevalence, clinical predictors, and immunopathogenesis remain incompletely understood. This study aimed to estimate the prevalence of ...