Beyond goal directed perfusion: Individualizing O2-delivery to O2-consumption

Sylvain Diop, Nicolas Mavambu, Maxime Aparicio, Antoine Premachandra, Jacques Thès, Department of Anesthesiology, Marie Lannelongue Hospital, Le Plessis Robinson, Cardiothoracic Intensive Care Unit, Marie Lannelongue Hospital, Le Plessis Robinson, Cardiothoracic Perfusion Team, Marie Lannelongue Hospital, Le Plessis Robinson, Department of Anesthesiology and Critical Care, European Hospital Georges Pompidou

Perfusion

Published online on March 10, 2026

Abstract

Perfusion, Ahead of Print.
Goal directed perfusion (GDP) aims to maintain an O2delivery above 270-300 ml/min/m2, during cardiopulmonary bypass. This strategy decreases the incidence of postoperative acute kidney injury. We first developed a simple physiological hypothesis that ...