Delivery of oxygen during cardiopulmonary bypass and associated clinical outcomes among adult cardiac surgery patients: A systematic review

Roger D. Dias, Paulo Borges, Geoffrey Rance, Rithy Srey, Lauren R. Kennedy Metz, Annette Martinez-Rioux, David Arney, Phani Paladugu, Ajami Gikandi, Christian Miccile, Ryan Harari, Kristina Iwai, Jennifer Fitzgerald, Paul O, Kenneth Shann, Matthew Gombolay, Marco A. Zenati, Medical AI , Cognitive Engineering , Department of Emergency Medicine, Mass General Brigham, Harvard Medical School, Cape Cod Healthcare, Psychology Department, Roanoke College, Division of Cardiac Surgery, Veterans Healthcare System, Sidney Kimmel Medical College, Thomas Jefferson University, Department of Radiology, Mass General Brigham, Division of Cardiac Surgery, Mass General Brigham

Perfusion

Published online on September 13, 2025

Abstract

Perfusion, Volume 41, Issue 5, Page 509-518, July 2026.
PurposeOxygen delivery (DO2) during cardiopulmonary bypass (CPB) is critical in preventing postoperative complications in adult cardiac surgery. This systematic review aimed to assess the relationship between intraoperative DO2during CPB, particularly ...