The lactate risk score (LRS): Anticipating hyperlactatemia during cardiopulmonary bypass

Ignazio Condello, Michele Dell, Serdar Gunaydin, Youssef El Dsouki, School of Medicine and Surgery, University of Insubria, Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, Department of Cardiovascular Surgery, University of Health Sciences, Ankara City Hospital Campus, Maastricht University Medical Centre

Perfusion

Published online on February 16, 2026

Abstract

Perfusion, Ahead of Print.
Hyperlactatemia during cardiopulmonary bypass (CPB) is a marker of inadequate oxygen delivery and correlates with postoperative morbidity and mortality. Although lactate is measured directly via enzymatic sensors, its rise can be anticipated through ...